It is a congenital disorder of skeletal muscle which is manifested by the significant increase in temperature (hyperthermia) up to 45°C, accelerated and irregular heart rate (tachycardia and arrhythmia), hyperventilation, muscle rigidity and may result in renal failure and death.
In genetically susceptible individuals, a particular group of volatile anesthetics may trigger the symptome. The inheritance of the disease is autosomal dominant.
Tested gene and mutation: RYR1, c.1640T>C
Breed: all breeds
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